Interaction Scheme

Molecule

Untitled
Agmatine

c = 0.0 — 5.0 µM

Host

Acyclic sodium 3 3' %28naphthalene 2 7 diyl%29bis%28propane 1 sulfonate%29 cucurbituril
Acyclic sodium 3,3'-(naphthalene-2,7-diyl)bis(p...

c = 3.0 µM

Indicator

Europium trinitrate hexahydrate
Europium trinitrate hexahydrate

c = 300.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka > 1.00⋅106 ± 2.00⋅105 M-1
Kd >
logKa > 6.0 ± 0.09
T 25.0 °C 298 K
Energy kJ mol-1 kcal mol-1
ΔG < -34.25 ± 0.5 -8.19 ± 0.12
These are the specifications of the determination of the experimental results.
Detection Method: Competitive
Assay Type: Competitive Binding Assay
Technique: Fluorescence
𝛌ex = 301.0 nm
𝛌em = 369.0 nm
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
pH 7.0
Please find here information about the dataset this interaction is part of.
Citation:

T. Minami, N. A. Esipenko, B. Zhang, L. Isaacs, P. Anzenbacher, SupraBank 2024, “Turn-on” fluorescent sensor array for basic amino acids in water (dataset). https://doi.org/10.34804/supra.202109281

Link: https://doi.org/10.34804/supra.202109281
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

T. Minami, N. A. Esipenko, B. Zhang, L. Isaacs, P. Anzenbacher, Chem. Commun. 2014, 50, 61–63.

Link: https://doi.org/10.1039/c3cc47416j
Export: BibTex | RIS | EndNote |

Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of Agmatine (2.0e-05 M) and Acyclic sodium 3,3'-(naphthalene-2,7-diyl)bis(propane-1-sulfonate) Cucurbituril (0 — 4.0e-05 M).