Interaction Scheme

Molecule

%28 %29 camphor
(-)-camphor

c = 2000.0 µM

Host

Alpha cd
α-CD

c = 0.0 — 1300.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 7.31⋅105 M-1
Kd =
logKa = 5.86
T 24.85 °C 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -33.47 -8.0
ΔH = -63.21 -15.11
-TΔS = 29.79 7.12
J mol-1 K-1 cal mol-1 K-1
ΔS = -100.0 -23.9
Comment
fitted data
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Isothermal Titration Calorimetry
Molecule: syringe
Partner: syringe
Detailed information about the solvation.
Solvent System Single Solvent
Solvent Deuterium Oxide
Please find here information about the dataset this interaction is part of.
Citation:

F. P. Schmidtchen, SupraBank 2024, The Anatomy of the Energetics of Molecular Recognition by Calorimetry: Chiral Discrimination of Camphor by α-Cyclodextrin (dataset). https://doi.org/10.34804/supra.20210928110

Link: https://doi.org/10.34804/supra.20210928110
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

F. P. Schmidtchen, Chemistry - A European Journal 2002, 8, 3522.

Link: https://doi.org/10.1002/1521-3765(20020802)8:15%3C3522::AID-CHEM3522%3E3.0.CO;2-X
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of (-)-camphor (2.7359781121751025e-05 M) and α-CD (0 — 5.471956224350205e-05 M).