Interaction

uncurated

Interaction Scheme

Molecule

Acridine hydrochloride
Acridine hydrochloride

Host

Cb8
CB8

Binding Properties

𝜈 Molecule 1 : 2 Host
Ka = 2.87⋅108 M-2
Kd =
logKa = 8.46
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -48.28 -11.54
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Isothermal Titration Calorimetry
Molecule: syringe
Partner: cell
Detailed information about the solvation.
Solvent System Single Solvent
Solvent
Please find here information about the dataset this interaction is part of.
Citation:

Z. Tao, X. Xiao, W. Xu, H. Feng, W. Zhao, C. Huang, C. Redshaw, SupraBank 2024, Amino acid recognition by a fluorescent chemosensor based on cucurbit[8]uril and acridine hydrochloride (dataset). https://doi.org/10.34804/supra.20220628442

Link: https://doi.org/10.34804/supra.20220628442
Export: BibTex | RIS | EndNote
Please find here information about the scholarly article describing the results derived from that data.
Citation:

W. Xu, H. Feng, W. Zhao, C. Huang, C. Redshaw, Z. Tao, X. Xiao, Analytica Chimica Acta 2020, 1135, 142–149.

Link: https://doi.org/10.1016/j.aca.2020.09.028
Export: BibTex | RIS | EndNote

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Acridine hydrochloride (6.968641114982578e-08 M) and CB8 (0 — 1.3937282229965157e-07 M).