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DOI:
https://doi.org/10.34804/supra.20210928210 Cc Cc by 4.0

Title:
Thermodynamic Analysis of Allosteric and Chelate Cooperativity in Di- and Trivalent Ammonium/Crown-Ether Pseudorotaxanes

https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/orlef7/2015/orlef7.2015.17.issue-20/acs.orglett.5b02592/20151013/images/large/ol-2015-02592x_0005.jpeg

Description:
A detailed thermodynamic analysis of the axle-wheel binding in di- and trivalent secondary ammonium/[24]crown-8 pseudorotaxanes is presented. Isothermal titration calorimetry (ITC) data and double mutant cycle analyses reveal an interesting interplay of positive as well as negative allosteric and positive chelate cooperativity thus providing profound insight into the effects governing multivalent binding in these pseudorotaxanes.

Citation:

K. Nowosinski, L. K. S. von Krbek, N. L. Traulsen, C. A. Schalley, SupraBank 2024, Thermodynamic Analysis of Allosteric and Chelate Cooperativity in Di- and Trivalent Ammonium/Crown-Ether Pseudorotaxanes (dataset). https://doi.org/10.34804/supra.20210928210

Link: https://doi.org/10.34804/supra.20210928210
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Citation:

K. Nowosinski, L. K. S. von Krbek, N. L. Traulsen, C. A. Schalley, Org. Lett. 2015, 17, 5076–5079.

Link: https://doi.org/10.1021/acs.orglett.5b02592
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Creators:
Orcidid | Ror | Karol Nowosinski
Orcidid | Ror | Larissa K. S. von Krbek
Orcidid | Ror | Nora L. Traulsen
Orcidid | Ror | Christoph A. Schalley

Contributers:
Orcidid | Ror | Laura Grimm | DataManager

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