Interactions of 50 mM deuterated sodium acetate buffer pD-4.7
Info |
|
Molecule |
|
Molecule |
|
Partner |
|
Partner |
|
Ka |
log Ka |
Conditions |
Supplement |
|
|
L-Phe
|
|
L-Phe
|
|
CB7
|
|
CB7
|
|
1.45⋅105 M-1
|
5.16
|
buffer
|
TMSP-d4
|
|
|
L-Phe
|
|
L-Phe
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
Amantadine
|
|
Amantadine
|
|
CB8
|
|
CB8
|
|
8.19⋅108 M-1
|
8.91
|
buffer
|
MDAP
|
|
|
Vecuronium
|
|
Vecuronium
|
|
CB7
|
|
CB7
|
|
4.80⋅1010 M-1
|
10.68
|
buffer
|
Tetramethyla...
|
|
|
1-Adamantylp...
|
|
1-Adamantylp...
|
|
CB8
|
|
CB8
|
|
2.00⋅109 M-1
|
9.3
|
buffer
|
Bis(aminomet...
|
|
|
1,4-Phenylen...
|
|
1,4-Phenylen...
|
|
CB7
|
|
CB7
|
|
2.07⋅106 M-1
|
6.32
|
buffer
|
TMSP-d4
|
|
|
Adamantane-1...
|
|
Adamantane-1...
|
|
CB7
|
|
CB7
|
|
2.06⋅108 M-1
|
8.31
|
buffer
|
TMSP-d4
|
|
|
TMSP-d4
|
|
TMSP-d4
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
Bis(aminomet...
|
|
Bis(aminomet...
|
|
CB7
|
|
CB7
|
|
1.78⋅107 M-1
|
7.25
|
buffer
|
(Aminomethyl...
|
|
|
(Aminomethyl...
|
|
(Aminomethyl...
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
(Aminomethyl...
|
|
(Aminomethyl...
|
|
CB7
|
|
CB7
|
|
8.88⋅108 M-1
|
8.95
|
buffer
|
TMSP-d4
|
|
|
Dimethyl-(4-...
|
|
Dimethyl-(4-...
|
|
CB7
|
|
CB7
|
|
5.18⋅107 M-1
|
7.71
|
buffer
|
TMSP-d4
|
|
|
p-Toluidine
|
|
p-Toluidine
|
|
CB7
|
|
CB7
|
|
8.38⋅106 M-1
|
6.92
|
buffer
|
TMSP-d4
|
|
|
(Ferrocen-1-...
|
|
(Ferrocen-1-...
|
|
CB7
|
|
CB7
|
|
3.31⋅1011 M-1
|
11.52
|
buffer
|
(Aminomethyl...
|
|
|
P-Xylylenedi...
|
|
P-Xylylenedi...
|
|
CB7
|
|
CB7
|
|
1.84⋅109 M-1
|
9.26
|
buffer
|
(Aminomethyl...
|
|
|
Rocuronium
|
|
Rocuronium
|
|
CB7
|
|
CB7
|
|
2.30⋅108 M-1
|
8.36
|
buffer
|
Tetramethyla...
|
|
|
1,2-Phenylen...
|
|
1,2-Phenylen...
|
|
CB7
|
|
CB7
|
|
8.04⋅104 M-1
|
4.91
|
buffer
|
TMSP-d4
|
|
|
Diamantane d...
|
|
Diamantane d...
|
|
CB7
|
|
CB7
|
|
1.90⋅1015 M-1
|
15.28
|
buffer
|
1-Adamantylp...
|
|
|
1-Adamantyl(...
|
|
1-Adamantyl(...
|
|
CB7
|
|
CB7
|
|
1.71⋅1012 M-1
|
12.23
|
buffer
|
1-Adamantylp...
|
|
|
Dimethyl-(4-...
|
|
Dimethyl-(4-...
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
p-Toluidine
|
|
p-Toluidine
|
|
CB6
|
|
CB6
|
|
8980.0 M-1
|
3.95
|
buffer
|
|
|
|
1,6-Hexanedi...
|
|
1,6-Hexanedi...
|
|
CB7
|
|
CB7
|
|
8.97⋅107 M-1
|
7.95
|
buffer
|
TMSP-d4
|
|
|
MDAP
|
|
MDAP
|
|
CB7
|
|
CB7
|
|
3.81⋅107 M-1
|
7.58
|
buffer
|
TMSP-d4
|
|
|
Pancuronium
|
|
Pancuronium
|
|
CB7
|
|
CB7
|
|
1.30⋅105 M-1
|
5.11
|
buffer
|
Tetramethyla...
|
|
|
1,3-Phenylen...
|
|
1,3-Phenylen...
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
1,6-Hexanedi...
|
|
1,6-Hexanedi...
|
|
CB6
|
|
CB6
|
|
4.49⋅108 M-1
|
8.65
|
buffer
|
CB7
|
|
|
1-Adamantylp...
|
|
1-Adamantylp...
|
|
CB7
|
|
CB7
|
|
1.98⋅1012 M-1
|
12.3
|
buffer
|
(Ferrocen-1-...
|
|
|
Bis(trimethy...
|
|
Bis(trimethy...
|
|
CB7
|
|
CB7
|
|
6.42⋅104 M-1
|
4.81
|
buffer
|
TMSP-d4
|
|
|
Pancuronium
|
|
Pancuronium
|
|
CB7
|
|
CB7
|
|
1.70⋅1010 M-1
|
10.23
|
buffer
|
Tetramethyla...
|
|
|
Memantine
|
|
Memantine
|
|
CB8
|
|
CB8
|
|
4.33⋅1011 M-1
|
11.64
|
buffer
|
Bis(aminomet...
|
|
|
TMSP-d4
|
|
TMSP-d4
|
|
CB8
|
|
CB8
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
P-Xylylenedi...
|
|
P-Xylylenedi...
|
|
CB6
|
|
CB6
|
|
550.0 M-1
|
2.74
|
buffer
|
|
|
|
1,2-Phenylen...
|
|
1,2-Phenylen...
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
TMSP-d4
|
|
TMSP-d4
|
|
CB7
|
|
CB7
|
|
1.82⋅107 M-1
|
7.26
|
buffer
|
1,3-Phenylen...
|
|
|
4,9-Diaminod...
|
|
4,9-Diaminod...
|
|
CB7
|
|
CB7
|
|
1.30⋅1011 M-1
|
11.11
|
buffer
|
Azanylpropyl...
|
|
|
1,4‐diaminoc...
|
|
1,4‐diaminoc...
|
|
CB7
|
|
CB7
|
|
2.27⋅107 M-1
|
7.36
|
buffer
|
TMSP-d4
|
|
|
Methyl viologen
|
|
Methyl viologen
|
|
CB7
|
|
CB7
|
|
1.32⋅107 M-1
|
7.12
|
buffer
|
TMSP-d4
|
|
|
Vecuronium
|
|
Vecuronium
|
|
CB7
|
|
CB7
|
|
2.20⋅105 M-1
|
5.34
|
buffer
|
Tetramethyla...
|
|
|
1,4-Phenylen...
|
|
1,4-Phenylen...
|
|
CB6
|
|
CB6
|
|
1860.0 M-1
|
3.27
|
buffer
|
|
|
|
Bis(aminomet...
|
|
Bis(aminomet...
|
|
CB8
|
|
CB8
|
|
5.78⋅1010 M-1
|
10.76
|
buffer
|
Amantadine
|
|
|
1-carboxyada...
|
|
1-carboxyada...
|
|
CB7
|
|
CB7
|
|
3.23⋅108 M-1
|
8.51
|
buffer
|
(Aminomethyl...
|
|
|
1-Adamantyl(...
|
|
1-Adamantyl(...
|
|
CB8
|
|
CB8
|
|
9.70⋅1010 M-1
|
10.99
|
buffer
|
Bis(aminomet...
|
|
|
3,4-Dihydrox...
|
|
3,4-Dihydrox...
|
|
CB6
|
|
CB6
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|
|
|
Amantadine
|
|
Amantadine
|
|
CB7
|
|
CB7
|
|
4.23⋅1012 M-1
|
12.63
|
buffer
|
1-Adamantylp...
|
|
|
Rocuronium
|
|
Rocuronium
|
|
CB7
|
|
CB7
|
|
1.50⋅104 M-1
|
4.18
|
buffer
|
Tetramethyla...
|
|
|
Memantine
|
|
Memantine
|
|
CB7
|
|
CB7
|
|
2.50⋅104 M-1
|
4.4
|
buffer
|
TMSP-d4
|
|
|
Pyridin-4-yl...
|
|
Pyridin-4-yl...
|
|
CB7
|
|
CB7
|
|
3.58⋅105 M-1
|
5.55
|
buffer
|
TMSP-d4
|
|
|
1,3-Phenylen...
|
|
1,3-Phenylen...
|
|
CB7
|
|
CB7
|
|
8.07⋅104 M-1
|
4.91
|
buffer
|
|
|
|
MDAP
|
|
MDAP
|
|
CB8
|
|
CB8
|
|
6.37⋅108 M-1
|
8.8
|
buffer
|
CB7
|
|
|
Pyridin-4-yl...
|
|
Pyridin-4-yl...
|
|
CB6
|
|
CB6
|
|
3000.0 M-1
|
3.48
|
buffer
|
|
|
|
Dopamine hyd...
|
|
Dopamine hyd...
|
|
CB7
|
|
CB7
|
|
4.32⋅104 M-1
|
4.64
|
buffer
|
TMSP-d4
|
|
|
Bis(trimethy...
|
|
Bis(trimethy...
|
|
CB8
|
|
CB8
|
|
1.11⋅1011 M-1
|
11.05
|
buffer
|
Bis(aminomet...
|
|
|
(Ferrocen-1-...
|
|
(Ferrocen-1-...
|
|
CB8
|
|
CB8
|
|
3.12⋅109 M-1
|
9.49
|
buffer
|
Bis(aminomet...
|
|
|
(Aminomethyl...
|
|
(Aminomethyl...
|
|
CB8
|
|
CB8
|
<
|
10.0 M-1
|
1.0
|
buffer
|
|