Interaction Scheme
Molecule
Neutral red hydrochloride
c = 40.0 µM
Host
heptakis-O-(2-hydroxypropyl)-β Cyclodextrin
c = 0.0 — 700.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1000.0 | ± | M-1 |
| Kd = | |||
| logKa = | |||
| T | 20.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -16.84 | ± 0.0 | -4.02 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 460.0 nm | ||
| 𝛌em | = | 575.0 nm | ||
| Ibound⁄Ifree | = | 23.0 | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 500 mM phosphate buffer pH-7.5 |
| Solvents | water | |
| Additives | phosphate | |
| Source of Concentration | estimated | |
| Total concentration | 50.0 mM | |
| pH | 7.5 |
Please find here information about the dataset this interaction is part of.
| Citation: |
G. Zhang, S. Shuang, Z. Dong, C. Dong, J. Pan, SupraBank 2024, Investigation on the inclusion behavior of neutral red with β-cyclodextrin, hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin (dataset). https://doi.org/10.34804/supra.20210928127 |
| Link: | https://doi.org/10.34804/supra.20210928127 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
G. Zhang, S. Shuang, Z. Dong, C. Dong, J. Pan, Analytica Chimica Acta 2002, 474, 189–195. |
| Link: | https://doi.org/10.1016/S0003-2670(02)01016-4 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Neutral red hydrochloride (0.02 M) and heptakis-O-(2-hydroxypropyl)-β Cyclodextrin (0 — 0.04 M).
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