Interaction Scheme

Molecule

Untitled
7-Methoxycoumarin

c = 30.0 µM

Host

Beta cd
β-CD

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 128.0 ± 32.0 M-1
Kd =
logKa = 2.11 ± 0.11
T 21.0 °C 294 K
Energy kJ mol-1 kcal mol-1
ΔG = -11.87 ± 0.62 -2.84 ± 0.15
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 320.0 nm
𝛌em = 395.0 nm
IboundIfree = 0.41
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

B. D. Wagner, S. J. Fitzpatrick, G. J. McManus, SupraBank 2024, Fluorescence Suppression of 7-Methoxycoumarin upon Inclusion into Cyclodextrins (dataset). https://doi.org/10.34804/supra.20210928397

Link: https://doi.org/10.34804/supra.20210928397
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

B. D. Wagner, S. J. Fitzpatrick, G. J. McManus, Journal of Inclusion Phenomena 2003, 47, 187–192.

Link: https://doi.org/10.1023/B:JIPH.0000011779.65838.44
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of 7-Methoxycoumarin (0.15625 M) and β-CD (0 — 0.3125 M).