Interaction Scheme
Molecule
Osthole
c = 75.0 µM
Host
β-CD
c = 0.0 — 8750.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 122.9 | ± | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -11.93 | ± 0.0 | -2.85 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 340.0 nm | ||
| 𝛌em | = | 400.0 nm | ||
| Ibound⁄Ifree | = | 2.6 | ||
Detailed information about the solvation.
| Solvent System | Single Solvent |
| Solvent | water |
Please find here information about the dataset this interaction is part of.
| Citation: |
H. Zhang, H. Zhang, C. Qu, L. Bai, L. Ding, SupraBank 2024, Fluorimetric and mass spectrometric study of the interaction of β-cyclodextrin and osthole (dataset). https://doi.org/10.34804/supra.20210928147 |
| Link: | https://doi.org/10.34804/supra.20210928147 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
H. Zhang, H. Zhang, C. Qu, L. Bai, L. Ding, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2007, 68, 474–477. |
| Link: | https://doi.org/10.1016/j.saa.2006.12.013 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Osthole (0.16273393002441008 M) and β-CD (0 — 0.32546786004882017 M).
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