Interaction Scheme
Molecule
Palmatine
c = 12.5 µM
Host
CB7
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 4.26⋅104 | ± 300.0 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -26.42 | ± 0.02 | -6.31 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 347.0 nm | ||
| 𝛌em | = | 497.0 nm | ||
| Ibound⁄Ifree | = | 8.2 | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 100 mM phosphate buffer pH-7.2 |
| Solvents | water | |
| Additives | Disodium phosph... | 66.6 mM |
| Sodium dihydro... | 33.4 mM | |
| Source of Concentration | real | |
| Total concentration | 100.0 mM | |
| pH | 7.2 |
Please find here information about the dataset this interaction is part of.
| Citation: |
C. Li, J. Li, X. Jia, SupraBank 2024, Selective binding and highly sensitive fluorescent sensor of palmatine and dehydrocorydaline alkaloids by cucurbit[7]uril (dataset). https://doi.org/10.34804/supra.20210928148 |
| Link: | https://doi.org/10.34804/supra.20210928148 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
C. Li, J. Li, X. Jia, Org. Biomol. Chem. 2009, 7, 2699. |
| Link: | https://doi.org/10.1039/B820852B |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Palmatine (0.00046948356807511736 M) and CB7 (0 — 0.0009389671361502347 M).
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