Interaction Scheme
Molecule
Sanguinarine
c = 1.0 µM
Host
CB5
c = 0.0 — 375.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.21⋅104 | ± | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -23.3 | ± 0.0 | -5.57 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 326.0 nm | ||
| 𝛌em | = | 541.0 nm | ||
| Ibound⁄Ifree | = | 6.0 | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 16 mM Britton–Robinson pH-1.8 |
| Solvents | water | |
| Additives | Phosphoric acid | |
| acetic acid | ||
| BORIC ACID | ||
| Sodium hydroxide | ||
| Source of Concentration | real | |
| Total concentration | 16.0 mM | |
| pH | 1.8 |
Please find here information about the dataset this interaction is part of.
| Citation: |
C. Li, L. Du, H. Zhang, SupraBank 2024, Study on the inclusion interaction of cucurbit[n]urils with sanguinarine by spectrofluorimetry and its analytical application (dataset). https://doi.org/10.34804/supra.20210928150 |
| Link: | https://doi.org/10.34804/supra.20210928150 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
C.-F. Li, L.-M. Du, H.-M. Zhang, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2010, 75, 912–917. |
| Link: | https://doi.org/10.1016/j.saa.2009.12.036 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Sanguinarine (0.001652892561983471 M) and CB5 (0 — 0.003305785123966942 M).
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