Interaction Scheme
Molecule
2,6-Dihydroxynaphthalene
c = 10.0 µM
Host
CB8
c = 120.0 µM
Cofactor
Methyl viologen
c = 120.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 7.30⋅105 | ± 6.00⋅104 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -33.47 | ± 0.2 | -8.0 | ± 0.05 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Associative Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 270.0 nm | ||
| 𝛌em | = | 370.0 nm | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 5 mM phosphate pH-7.4 |
| Solvents | water | |
| Source of Concentration | real | |
| Total concentration | 5.0 mM | |
| pH | 7.4 |
Please find here information about the dataset this interaction is part of.
| Citation: |
A. R. Urbach, V. Ramalingam, SupraBank 2025, Cucurbit[8]uril Rotaxanes (dataset). https://doi.org/10.34804/supra.20210928104 |
| Link: | https://doi.org/10.34804/supra.20210928104 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
V. Ramalingam, A. R. Urbach, Org. Lett. 2011, 13, 4898–4901. |
| Link: | https://doi.org/10.1021/ol201991e |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of 2,6-Dihydroxynaphthalene (2.7397260273972603e-05 M) and CB8 (0 — 5.479452054794521e-05 M).
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