Interaction Scheme
Molecule
L-Trp
c = 50.0 µM
Host
Methyl CB8-Viologen-Rotaxane
c = 0.0 — 1000.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.80⋅104 | ± 2000.0 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -24.29 | ± 0.28 | -5.81 | ± 0.07 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 280.0 nm | ||
| 𝛌em | = | 350.0 nm | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 5 mM phosphate pH-7.4 |
| Solvents | water | |
| Source of Concentration | real | |
| Total concentration | 5.0 mM | |
| pH | 7.4 |
Please find here information about the dataset this interaction is part of.
| Citation: |
A. R. Urbach, V. Ramalingam, SupraBank 2025, Cucurbit[8]uril Rotaxanes (dataset). https://doi.org/10.34804/supra.20210928104 |
| Link: | https://doi.org/10.34804/supra.20210928104 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
V. Ramalingam, A. R. Urbach, Org. Lett. 2011, 13, 4898–4901. |
| Link: | https://doi.org/10.1021/ol201991e |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of L-Trp (0.0011111111111111111 M) and Methyl CB8-Viologen-Rotaxane (0 — 0.0022222222222222222 M).
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