Interaction Scheme
Molecule
L-Trp
Host
CB8
Binding Properties
| 𝜈 | Molecule 2 : 1 Host | ||
| Ka = | 6.90⋅107 | ± 1.30⋅107 | M-2 |
| Kd = | |||
| logKa = | |||
| T | 27.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -45.04 | ± 0.48 | -10.76 | ± 0.11 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | ||
| Assay Type: | Direct Binding Assay | ||
| Technique: | Isothermal Titration Calorimetry | ||
| Instrument: | MircoCal VP-ITC | ||
| VCell | = | 1400.0 𝜇L | |
| VSyringe | = | 350.0 𝜇L | |
| Molecule: | syringe | ||
| Partner: | cell | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 10 mM phosphate pH-7.0 |
| Solvents | water | |
| Source of Concentration | ||
| Total concentration | 10.0 mM | |
| pH | 7.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
P. Rajgariah, A. R. Urbach, SupraBank 2024, Scope of amino acid recognition by cucurbit[8]uril (dataset). https://doi.org/10.34804/supra.20210928384 |
| Link: | https://doi.org/10.34804/supra.20210928384 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
P. Rajgariah, A. R. Urbach, J Incl Phenom Macrocycl Chem 2008, 62, 251–254. |
| Link: | https://doi.org/10.1007/s10847-008-9464-y |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of L-Trp (2.898550724637681e-07 M) and CB8 (0 — 5.797101449275362e-07 M).
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