Interaction Scheme
Molecule
Acridine (protonated)
c = 5.7 µM
Host
CB7
c = 0.0 — 150.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.80⋅106 | ± 4.00⋅105 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| kin= | ± | M-1s-1 | |
| kout= | 0.0 | ± | s-1 |
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -35.71 | ± 0.56 | -8.53 | ± 0.13 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌em | = | 477.0 nm | ||
Detailed information about the solvation.
| Solvent System | Complex Mixture |
| Solvents | water |
| Additives | hydrochloric acid |
| pH | 3.5 |
Please find here information about the dataset this interaction is part of.
| Citation: |
A. Bhasikuttan, J. Mohanty, R. Khurana, N. Barooah, SupraBank 2025, Modulation in the acidity constant of acridine dye with cucurbiturils: stimuli-responsive pKa tuning and dye relocation into live cells (dataset). https://doi.org/10.34804/supra.20210928206 |
| Link: | https://doi.org/10.34804/supra.20210928206 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
R. Khurana, N. Barooah, A. C. Bhasikuttan, J. Mohanty, Org. Biomol. Chem. 2017, 15, 8448–8457. |
| Link: | https://doi.org/10.1039/C7OB02135F |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Acridine (protonated) (1.1111111111111112e-05 M) and CB7 (0 — 2.2222222222222223e-05 M).
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