Interaction Scheme
Molecule
Epiberberine
c = 0.038 µM
Host
CB7
c = 0.0 — 0.12 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 6.20⋅108 | M-1 | |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| kin= | 69000000.0 | ± 8000000.0 | M-1s-1 |
| kout= | 0.1 | ± 0.02 | s-1 |
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -50.19 | -12.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌em | = | 527.0 nm | ||
Detailed information about the solvation.
| Solvent System | Single Solvent |
| Solvent | water |
Please find here information about the dataset this interaction is part of.
| Citation: |
L. Biczok, Z. Miskolczy, G. Lendvay, SupraBank 2024, Substituent effect on the dynamics of the inclusion complex formation between protoberberine alkaloids and cucurbit[7]uril (dataset). https://doi.org/10.34804/supra.20210928143 |
| Link: | https://doi.org/10.34804/supra.20210928143 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
Z. Miskolczy, L. Biczók, G. Lendvay, Phys. Chem. Chem. Phys. 2018, 20, 15986–15994. |
| Link: | https://doi.org/10.1039/C8CP01845F |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Epiberberine (3.2258064516129035e-08 M) and CB7 (0 — 6.451612903225807e-08 M).
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