Interaction Scheme
Molecule
Asymmetric dimethylarginine
c = 1500.0 µM
Host
sCx6
c = 0.0 — 16300.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 315.0 | ± 82.0 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 23.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -14.16 | ± 0.66 | -3.38 | ± 0.16 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | ||
| Assay Type: | Direct Binding Assay | ||
| Technique: | Nuclear Magnetic Resonance | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 40 mM deuterated phosphate pD-7.4 |
| Solvents | Deuterium Oxide | 100.0 % |
| Additives | Disodium hydrog... | 30.2 mM |
| Sodium dihydrog... | 9.8 mM | |
| Source of Concentration | ||
| Total concentration | 40.0 mM | |
| pH | 7.4 |
Please find here information about the dataset this interaction is part of.
| Citation: |
K. D. Daze, F. Hof, C. S. Beshara, C. E. Jones, B. J. Lilgert, SupraBank 2025, Determining the effects of salt, buffer, and temperature on the complexation of methylated ammonium ions and methyllysines by sulfonated calixarenes (dataset). https://doi.org/10.34804/supra.2021092877 |
| Link: | https://doi.org/10.34804/supra.2021092877 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
K. D. Daze, C. E. Jones, B. J. Lilgert, C. S. Beshara, F. Hof, Can. J. Chem. 2013, 91, 1072–1076. |
| Link: | https://doi.org/10.1139/cjc-2013-0186 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Asymmetric dimethylarginine (0.06349206349206349 M) and sCx6 (0 — 0.12698412698412698 M).
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