Interaction Scheme
Molecule
perfluorooctanoic acid
c = 0.0 — 7.6 µM
Host
gCx5-6C
c = 0.4 µM
Indicator
Uranine
c = 0.5 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.70⋅107 | ± 3.00⋅106 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -41.27 | ± 0.44 | -9.86 | ± 0.11 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Competitive | ||
| Assay Type: | Competitive Binding Assay | ||
| Technique: | Fluorescence | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 10 mM HEPES pH-7.4 |
| Solvents | water | 100.0 % |
| Additives | Hepes | 10.0 mM |
| Source of Concentration | ||
| Total concentration | 10.0 mM | |
| pH | 7.4 |
Please find here information about the dataset this interaction is part of.
| Citation: |
X. Hu, D. Guo, Y. Wang, Z. Zheng, W. Geng, H. Yu, Z. Li, Y. Wang, SupraBank 2025, Guanidinocalix[5]arene for sensitive fluorescence detection and magnetic removal of perfluorinated pollutants (dataset). https://doi.org/10.34804/supra.20210928190 |
| Link: | https://doi.org/10.34804/supra.20210928190 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
Z. Zheng, H. Yu, W.-C. Geng, X.-Y. Hu, Y.-Y. Wang, Z. Li, Y. Wang, D.-S. Guo, Nat Commun 2019, 10, DOI 10.1038/s41467-019-13775-1. |
| Link: | https://doi.org/10.1038/s41467-019-13775-1 |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of perfluorooctanoic acid (1.176470588235294e-06 M) and gCx5-6C (0 — 2.352941176470588e-06 M).
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