Interaction Scheme
Molecule
1,8-ANS
c = 1.0 µM
Host
gCx5-6C
c = 0.0 — 3.19 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 3.00⋅106 | ± 6.00⋅105 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -36.97 | ± 0.5 | -8.84 | ± 0.12 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 350.0 nm | ||
| 𝛌em | = | 470.0 nm | ||
| Ibound⁄Ifree | = | 25.0 | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 10 mM HEPES pH-7.4 |
| Solvents | water | 100.0 % |
| Additives | Hepes | 10.0 mM |
| Source of Concentration | ||
| Total concentration | 10.0 mM | |
| pH | 7.4 |
Please find here information about the dataset this interaction is part of.
| Citation: |
D. Guo, Y. Wang, Z. Zheng, H. Sun, Y. Kong, W. Geng, Z. Zhao, SupraBank 2024, Complexation of a guanidinium-modified calixarene with diverse dyes and investigation of the corresponding photophysical response (dataset). https://doi.org/10.34804/supra.20210928352 |
| Link: | https://doi.org/10.34804/supra.20210928352 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
Y.-Y. Wang, Y. Kong, Z. Zheng, W.-C. Geng, Z.-Y. Zhao, H. Sun, D.-S. Guo, Beilstein J. Org. Chem. 2019, 15, 1394–1406. |
| Link: | https://doi.org/10.3762/bjoc.15.139 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of 1,8-ANS (6.666666666666667e-06 M) and gCx5-6C (0 — 1.3333333333333333e-05 M).
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