Interaction

curated

Interaction Scheme

Molecule

Untitled
P-TPE

c = 1.0 µM

Host

Gc5a
gCx5-6C

c = 0.0 — 1.65 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 8.40⋅107 ± 1.10⋅107 M-1
Kd =
logKa = 7.92 ± 0.06
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -45.23 ± 0.33 -10.81 ± 0.08
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 327.0 nm
𝛌em = 473.0 nm
Detailed information about the solvation.
Solvent System Buffer System 10 mM HEPES pH-7.4
Solvents water 100.0 %
Additives Hepes 10.0 mM
Source of Concentration
Total concentration 10.0 mM
pH 7.4
Please find here information about the dataset this interaction is part of.
Citation:

D. Guo, Y. Wang, Z. Zheng, H. Sun, Y. Kong, W. Geng, Z. Zhao, SupraBank 2024, ["Complexation of a guanidinium-modified calixarene with diverse dyes and investigation of the corresponding photophysical response"] (dataset). https://doi.org/10.34804/supra.20210928158

Link: https://doi.org/10.34804/supra.20210928158
Export: BibTex | RIS | EndNote
Please find here information about the scholarly article describing the results derived from that data.
Citation:

Y.-Y. Wang, Y. Kong, Z. Zheng, W.-C. Geng, Z.-Y. Zhao, H. Sun, D.-S. Guo, Beilstein Journal of Organic Chemistry 2019, 15, 1394–1406.

Link: https://doi.org/10.3762/bjoc.15.139%C2%A0

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of P-TPE (2.380952380952381e-07 M) and gCx5-6C (0 — 4.761904761904762e-07 M).