Interaction Scheme

Molecule

Gly l phe
Gly-L-Phe

Host

Scx6 sodium salt
sCx6-sodium salt

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 1905.46 ± 87.78 M-1
Kd =
logKa = 3.28 ± 0.02
T 25.0 °C 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -18.72 ± 0.11 -4.47 ± 0.03
ΔH = -46.9 ± 1.1 -11.21 ± 0.26
-TΔS = 28.1 ± 1.1 6.72 ± 0.26
J mol-1 K-1 cal mol-1 K-1
ΔS = -94.2 ± 3.7 -22.5 ± 0.9
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Isothermal Titration Calorimetry
Molecule: syringe
Partner: syringe
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

H. Buschmann, L. Mutihac, E. Schollmeyer, SupraBank 2024, Complexation of Some Amino Acids and Peptides by p-Sulfonatocalix[4]arene and Hexasodium p-Sulfonatocalix[6]arene in Aqueous Solution (dataset). https://doi.org/10.34804/supra.20210928235

Link: https://doi.org/10.34804/supra.20210928235
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

H.-J. Buschmann, L. Mutihac, E. Schollmeyer, Journal of Inclusion Phenomena and Macrocyclic Chemistry 2003, 46, 133–137.

Link: https://doi.org/10.1023/A:1026361017680
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of Gly-L-Phe (0.010496153159866909 M) and sCx6-sodium salt (0 — 0.020992306319733818 M).