Interaction

curated

Interaction Scheme

Molecule

Quinine
Quinine

Host

Scx4 thia
stCx4

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 2.80⋅105 ± 1.00⋅104 M-1
Kd =
logKa = 5.45 ± 0.02
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -31.09 ± 0.09 -7.43 ± 0.02
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 329.0 nm
Detailed information about the solvation.
Solvent System Complex Mixture
Solvents water
Additives hydrochloric acid
pH 2.0
Please find here information about the dataset this interaction is part of.
Citation:

D. Guo, Y. Liu, L. Wang, P. Du, J. Yang, SupraBank 2024, Binding behaviour and solubilisation of p-sulfonatocalixarenes to cinchona alkaloids (dataset). https://doi.org/10.34804/supra.2021092830

Link: https://doi.org/10.34804/supra.2021092830
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

L.-H. Wang, P. Du, J. Yang, D.-S. Guo, Y. Liu, Supramolecular Chemistry 2014, 26, 809–816.

Link: https://doi.org/10.1080/10610278.2014.882509
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Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Quinine (7.142857142857143e-05 M) and stCx4 (0 — 0.00014285714285714287 M).