Interaction Scheme

Molecule

Norfloxacin
Norfloxacin

Host

Scx6
sCx6

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 3.58⋅104 M-1
Kd =
logKa = 4.55
T 25.0 °C 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -25.99 -6.21
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 305.0 nm
Detailed information about the solvation.
Solvent System Buffer System 500 mM phosphate pH-8.0
Solvents water
Additives Disodium hydrog...
Sodium hydroxide
Sodium dihydrog...
Source of Concentration
Total concentration 500.0 mM
pH 8.0
Please find here information about the dataset this interaction is part of.
Citation:

J. Chao, K. Song, H. Wang, Z. Guo, B. Zhang, T. Zhang, SupraBank 2024, Study on the inclusion interaction of p-sulfonatocalix[n]arenes with norfloxacin (dataset). https://doi.org/10.34804/supra.2021092884

Link: https://doi.org/10.34804/supra.2021092884
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

J. Chao, K. Song, H. Wang, Z. Guo, B. Zhang, T. Zhang, Physics and Chemistry of Liquids 2016, 55, 579–588.

Link: https://doi.org/10.1080/00319104.2016.1250270
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of Norfloxacin (0.0005586592178770949 M) and sCx6 (0 — 0.0011173184357541898 M).