Interaction

curated

Interaction Scheme

Molecule

Untitled
ACh

Host

Cx4
Cx4

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 7.00⋅104 ± 1.00⋅104 M-1
Kd =
logKa = 4.85 ± 0.06
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -27.66 ± 0.36 -6.61 ± 0.09
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Nuclear Magnetic Resonance
Nucleus 1H
Detailed information about the solvation.
Solvent System Buffer System 100 mM phosphate pH-7.3
Solvents water
Source of Concentration
pH 7.3
Please find here information about the dataset this interaction is part of.
Citation:

H. Bakirci, W. M. Nau, SupraBank 2024, Fluorescence Regeneration as a Signaling Principle for Choline and Carnitine Binding: A Refined Supramolecular Sensor System Based on a Fluorescent Azoalkane (dataset). https://doi.org/10.34804/supra.20210928371

Link: https://doi.org/10.34804/supra.20210928371
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

H. Bakirci, W. M. Nau, Adv. Funct. Mater. 2006, 16, 237–242.

Link: https://doi.org/10.1002/adfm.200500219
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Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of ACh (0.00028571428571428574 M) and Cx4 (0 — 0.0005714285714285715 M).