Interaction Scheme
Molecule
Lucigenin
c = 1.0 µM
Host
sMeCx5
c = 0.0 — 8.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.61⋅106 | ± 3.00⋅104 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -35.43 | ± 0.05 | -8.47 | ± 0.01 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 360.0 nm | ||
| 𝛌em | = | 504.0 nm | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 10 mM phosphate pH-8.0 |
| Solvents | water | |
| Additives | Sodium dihydrog... | 10.0 mM |
| Sodium hydroxide | ||
| Source of Concentration | estimated | |
| Total concentration | 10.0 mM | |
| pH | 8.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
D. Guo, Y. Liu, J. Yang, SupraBank 2025, Specifically Monitoring Butyrylcholinesterase by Supramolecular Tandem Assay (dataset). https://doi.org/10.34804/supra.20210928273 |
| Link: | https://doi.org/10.34804/supra.20210928273 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
D.-S. Guo, J. Yang, Y. Liu, Chem. Eur. J. 2013, 19, 8755–8759. |
| Link: | https://doi.org/10.1002/chem.201300980 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Lucigenin (1.2422360248447205e-05 M) and sMeCx5 (0 — 2.484472049689441e-05 M).
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