Interaction

curated

Interaction Scheme

Molecule

Toluidine blue
Toluidine Blue

c = 3.42 µM

Host

Beta cd
β-CD

c = 0.0 — 4230.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 442.0 ± 44.2 M-1
Kd =
logKa = 2.65 ± 0.04
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -15.1 ± 0.25 -3.61 ± 0.06
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 595.0 nm
𝛌em = 630.0 nm
Ibound⁄Ifree = 3.0
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

M. Ilanchelian, C. Retna Raj, R. Ramaraj, SupraBank 2024, Spectral Studies on the Cyclodextrin Inclusion Complexes of Toluidine Blue O and Meldola's Blue in Aqueous Solution - Journal of Inclusion Phenomena and Macrocyclic Chemistry (dataset). https://doi.org/10.34804/supra.20211007404

Link: https://doi.org/10.34804/supra.20211007404
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

M. Ilanchelian, C. Retna Raj, R. Ramaraj, Journal of Inclusion Phenomena and Macrocyclic Chemistry 2000, 36, 9–20.

Link: https://doi.org/10.1023/A:1008085829227
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Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Toluidine Blue (0.04524886877828054 M) and β-CD (0 — 0.09049773755656108 M).