Interaction Scheme
Molecule
Citrate
c = 0.0 — 600.0 µM
Host
i-Cx4-3C
c = 1000.0 µM
Cofactor
1,8-naphthalimide dicarboxylate
c = 5.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 6.26⋅104 | ± 1700.0 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 24.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -27.29 | ± 0.07 | -6.52 | ± 0.02 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Associative Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 350.0 nm | ||
| 𝛌em | = | 398.0 nm | ||
Detailed information about the solvation.
| Solvent System | Single Solvent |
| Solvent | water |
| pH | 7.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
W. M. Nau, U. Pischel, A. L. Koner, J. Schatz, SupraBank 2025, Selective Sensing of Citrate by a Supramolecular 1,8-Naphthalimide/Calix[4]arene Assembly via Complexation-Modulated pKaShifts in a Ternary Complex (dataset). https://doi.org/10.34804/supra.20210928287 |
| Link: | https://doi.org/10.34804/supra.20210928287 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
A. L. Koner, J. Schatz, W. M. Nau, U. Pischel, J. Org. Chem. 2007, 72, 3889–3895. |
| Link: | https://doi.org/10.1021/jo070268+ |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Citrate (0.0003194888178913738 M) and i-Cx4-3C (0 — 0.0006389776357827476 M).
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