Interaction

curated

Interaction Scheme

Molecule

Toluidine blue
Toluidine Blue

c = 3.42 µM

Host

Gamma cd
γ-CD

c = 0.0 — 616.0 µM

Binding Properties

𝜈 Molecule 2 : 1 Host
Ka = 2527.0 ± 252.7 M-2
Kd =
logKa = 3.4 ± 0.04
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -19.42 ± 0.25 -4.64 ± 0.06
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 595.0 nm
𝛌em = 630.0 nm
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

M. Ilanchelian, C. Retna Raj, R. Ramaraj, SupraBank 2024, Spectral Studies on the Cyclodextrin Inclusion Complexes of Toluidine Blue O and Meldola's Blue in Aqueous Solution - Journal of Inclusion Phenomena and Macrocyclic Chemistry (dataset). https://doi.org/10.34804/supra.20211007404

Link: https://doi.org/10.34804/supra.20211007404
Export: BibTex | RIS | EndNote
Please find here information about the scholarly article describing the results derived from that data.
Citation:

M. Ilanchelian, C. Retna Raj, R. Ramaraj, Journal of Inclusion Phenomena and Macrocyclic Chemistry 2000, 36, 9–20.

Link: https://doi.org/10.1023/A:1008085829227
Export: BibTex | RIS | EndNote

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Toluidine Blue (0.007914523149980214 M) and γ-CD (0 — 0.015829046299960427 M).