Interaction Scheme

Molecule

%28 %29 camphor
(-)-camphor

c = 2000.0 µM

Host

Alpha cd
α-CD

c = 0.0 — 1290.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 4.49⋅105 M-1
Kd =
logKa = 5.65
T 20.42 °C 294 K
Energy kJ mol-1 kcal mol-1
ΔG = -31.17 -7.45
ΔH = -65.56 -15.67
-TΔS = 33.79 8.08
J mol-1 K-1 cal mol-1 K-1
ΔS = -115.1 -27.5
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Isothermal Titration Calorimetry
Molecule: syringe
Partner: syringe
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

F. P. Schmidtchen, SupraBank 2024, The Anatomy of the Energetics of Molecular Recognition by Calorimetry: Chiral Discrimination of Camphor by α-Cyclodextrin (dataset). https://doi.org/10.34804/supra.20210928110

Link: https://doi.org/10.34804/supra.20210928110
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

F. P. Schmidtchen, Chemistry - A European Journal 2002, 8, 3522.

Link: https://doi.org/10.1002/1521-3765(20020802)8:15%3C3522::AID-CHEM3522%3E3.0.CO;2-X
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of (-)-camphor (4.4543429844097995e-05 M) and α-CD (0 — 8.908685968819599e-05 M).