Interaction Scheme

Molecule

%28 %29 camphor
(+)-camphor

c = 2000.0 µM

Host

Alpha cd
α-CD

c = 0.0 — 1600.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 2.19⋅105 M-1
Kd =
logKa = 5.34
T 40.17 °C 313 K
Energy kJ mol-1 kcal mol-1
ΔG = -32.04 -7.66
ΔH = -80.03 -19.13
-TΔS = 47.99 11.47
J mol-1 K-1 cal mol-1 K-1
ΔS = -153.2 -36.6
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Isothermal Titration Calorimetry
Molecule: syringe
Partner: syringe
Detailed information about the solvation.
Solvent System Single Solvent
Solvent Deuterium Oxide
Please find here information about the dataset this interaction is part of.
Citation:

F. P. Schmidtchen, SupraBank 2024, The Anatomy of the Energetics of Molecular Recognition by Calorimetry: Chiral Discrimination of Camphor by α-Cyclodextrin (dataset). https://doi.org/10.34804/supra.20210928110

Link: https://doi.org/10.34804/supra.20210928110
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

F. P. Schmidtchen, Chemistry - A European Journal 2002, 8, 3522.

Link: https://doi.org/10.1002/1521-3765(20020802)8:15%3C3522::AID-CHEM3522%3E3.0.CO;2-X
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of (+)-camphor (9.132420091324201e-05 M) and α-CD (0 — 0.00018264840182648402 M).