Interaction Scheme
Molecule
triclosan
c = 25.0 µM
Host
Hydroxypropyl-β-Cyclodextrin
c = 250.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 9.60⋅106 | ± 4.20⋅106 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -39.86 | ± 1.16 | -9.53 | ± 0.28 |
| ΔH | = | -521.0 | ± 9.0 | -124.52 | ± 2.15 |
| -TΔS | = | 478.0 | ± 0.0 | 114.24 | ± 0.0 |
| J mol-1 K-1 | cal mol-1 K-1 | ||||
| ΔS | = | -1603.2 | ± 0.0 | -383.2 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | ||
| Assay Type: | Direct Binding Assay | ||
| Technique: | Isothermal Titration Calorimetry | ||
| Molecule: | syringe | ||
| Partner: | cell | ||
Detailed information about the solvation.
| Solvent System | Single Solvent |
| Solvent | water |
Please find here information about the dataset this interaction is part of.
| Citation: |
A. Celebioglu, T. Uyar, SupraBank 2024, Electrospinning of Polymer-free Nanofibers from Cyclodextrin Inclusion Complexes (dataset). https://doi.org/10.34804/supra.20220628437 |
| Link: | https://doi.org/10.34804/supra.20220628437 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
A. Celebioglu, T. Uyar, Langmuir 2011, 27, 6218–6226. |
| Link: | https://doi.org/10.1021/la1050223 |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of triclosan (2.0833333333333334e-06 M) and Hydroxypropyl-β-Cyclodextrin (0 — 4.166666666666667e-06 M).
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