Interaction

curated

Interaction Scheme

Molecule

3 6 diaminoacridin 10 ium
Proflavine

c = 1.0 µM

Host

Cb8
CB8

c = 0.0 — 6.25 µM

Binding Properties

𝜈 Molecule 2 : 1 Host
Ka = 2.12⋅1015 ± 5.90⋅1014 M-2
Kd =
logKa = 15.33 ± 0.12
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -87.48 ± 0.71 -20.91 ± 0.17
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
Detailed information about the solvation.
Solvent System Complex Mixture
Solvents water
Additives hydrochloric acid
pH 5.5
Please find here information about the dataset this interaction is part of.
Citation:

P. Montes-Navajas, A. Corma, H. Garcia, SupraBank 2024, Complexation and Fluorescence of Tricyclic Basic Dyes Encapsulated in Cucurbiturils (dataset). https://doi.org/10.34804/supra.2021092824

Link: https://doi.org/10.34804/supra.2021092824
Export: BibTex | RIS | EndNote
Please find here information about the scholarly article describing the results derived from that data.
Citation:

P. Montes-Navajas, A. Corma, H. Garcia, ChemPhysChem 2008, 9, 713–720.

Link: https://doi.org/10.1002/cphc.200700735
Export: BibTex | RIS | EndNote

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Proflavine (9.433962264150944e-15 M) and CB8 (0 — 1.8867924528301888e-14 M).