Interaction Scheme

Molecule

A
Erythrosin B

Host

Heptakis o %282 hydroxypropyl%29 beta cyclodextrin
heptakis-O-(2-hydroxypropyl)-β Cyclodextrin

c = 800.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 189.0 ± 13.0 M-1
Kd =
logKa = 2.28 ± 0.03
T 25.0 °C 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -12.99 ± 0.17 -3.1 ± 0.04
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 520.0 nm
𝛌em = 549.0 nm
IboundIfree = 1.18
Detailed information about the solvation.
Solvent System Buffer System ammonium chloride pH-11.3
Solvents water
Additives AMMONIUM CHLORIDE
Source of Concentration
pH 11.3
Please find here information about the dataset this interaction is part of.
Citation:

X. ZHU, J. SUN, J. WU, SupraBank 2024, Study on the inclusion interactions of β-cyclodextrin and its derivative with dyes by spectrofluorimetry and its analytical application (dataset). https://doi.org/10.34804/supra.20210928302

Link: https://doi.org/10.34804/supra.20210928302
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

X. ZHU, J. SUN, J. WU, Talanta 2007, 72, 237–242.

Link: https://doi.org/10.1016/j.talanta.2006.10.016
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Binding Isotherm Simulations


The plot depicts the binding isotherm simulation of a 1:1 interaction of Erythrosin B (0.10582010582010581 M) and heptakis-O-(2-hydroxypropyl)-β Cyclodextrin (0 — 0.21164021164021163 M).