Interaction Scheme
Molecule
1-adamantane carboxylate
Host
α-CD
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 2.86⋅10-04 | M-1 | |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | 20.23 | 4.84 | ||
| ΔH | = | -14.6 | -3.49 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | ||
| Assay Type: | Direct Binding Assay | ||
| Technique: | Isothermal Titration Calorimetry | ||
| Molecule: | syringe | ||
| Partner: | cell | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 30 mM phosphate pH-7.2 |
| Solvents | water | |
| Additives | Disodium phosph... | 20.0 mM |
| Sodium dihydrog... | 10.0 mM | |
| Source of Concentration | real | |
| Total concentration | 30.0 mM | |
| pH | 7.2 |
Please find here information about the dataset this interaction is part of.
| Citation: |
J. C. Harrison, M. R. Eftink, SupraBank 2024, Cyclodextrin-adamantanecarboxylate inclusion complexes: A model system for the hydrophobic effect (dataset). https://doi.org/10.34804/supra.20210928266 |
| Link: | https://doi.org/10.34804/supra.20210928266 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
J. C. Harrison, M. R. Eftink, Biopolymers 1982, 21, 1153–1166. |
| Link: | https://doi.org/10.1002/bip.360210611 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of 1-adamantane carboxylate (70003.50017500875 M) and α-CD (0 — 140007.0003500175 M).
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