Interaction

curated

Interaction Scheme

Molecule

Palmatine
Palmatine

c = 12.5 µM

Host

Cb7
CB7

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 9.10⋅105 ± 8000.0 M-1
Kd =
logKa = 5.96 ± 0.0
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -34.01 ± 0.02 -8.13 ± 0.0
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 347.0 nm
𝛌em = 497.0 nm
Ibound⁄Ifree = 8.2
Detailed information about the solvation.
Solvent System Complex Mixture
Solvents water 96.0 %
ethanol 4.0 %
Total concentration 0.0 mM
Please find here information about the dataset this interaction is part of.
Citation:

C. Li, J. Li, X. Jia, SupraBank 2024, Selective binding and highly sensitive fluorescent sensor of palmatine and dehydrocorydaline alkaloids by cucurbit[7]uril (dataset). https://doi.org/10.34804/supra.20210928148

Link: https://doi.org/10.34804/supra.20210928148
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

C. Li, J. Li, X. Jia, Org. Biomol. Chem. 2009, 7, 2699.

Link: https://doi.org/10.1039/B820852B
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Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Palmatine (2.1978021978021977e-05 M) and CB7 (0 — 4.3956043956043955e-05 M).