Interaction Scheme
Molecule
Indole
c = 0.0 — 100.0 µM
Host
Rotaxane
c = 2.5 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 3.02⋅105 | M-1 | |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -31.28 | -7.48 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 393.0 nm | ||
| 𝛌em | = | 450.0 nm | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 1X PBS pH-7.4 |
| Solvents | water | |
| Additives | sodium chloride | 137.0 mM |
| Disodium hydrog... | 10.0 mM | |
| potassium chloride | 2.7 mM | |
| Potassium dihyd... | 1.8 mM | |
| Source of Concentration | real | |
| Total concentration | 151.5 mM | |
| pH | 7.4 |
Please find here information about the dataset this interaction is part of.
| Citation: |
J. Krämer, SupraBank 2024, A supramolecular CB8-β-CD-rotaxane chemosensor for the optical detection of tryptophan in human serum and urine (dataset). https://doi.org/10.34804/supra.20220128415 |
| Link: | https://doi.org/10.34804/supra.20220128415 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
|
| Link: | https://suprabank.org/datasets/415 |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Indole (6.622516556291391e-05 M) and Rotaxane (0 — 0.00013245033112582781 M).
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