Interaction Scheme
Molecule
L-cysteine
c = 0.0 — 600.0 µM
Host
cyclometalated [N,C,N-Pt(II)] framework
c = 50.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 7.94⋅104 | ± 1830.0 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -27.97 | ± 0.06 | -6.68 | ± 0.01 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 424.0 nm | ||
| 𝛌em | = | 504.0 nm | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 8:2 DMF/Tris Buffer, pH 7.2 |
| Solvents | DMF | 80.0 % |
| water | 20.0 % | |
| Additives | Trometamol | |
| Source of Concentration | ||
| pH | 7.2 |
Please find here information about the dataset this interaction is part of.
| Citation: |
W. Tong, M. C. W. Chan, S. Yiu, SupraBank 2024, Congested Cyclometalated Platinum(II) Ditopic Frameworks and Their Phosphorescent Responses to S-Containing Amino Acids (dataset). https://doi.org/10.34804/supra.20220628444 |
| Link: | https://doi.org/10.34804/supra.20220628444 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
W.-L. Tong, M. C. W. Chan, S.-M. Yiu, Organometallics 2010, 29, 6377–6383. |
| Link: | https://doi.org/10.1021/om1007488 |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of L-cysteine (0.0002517940324814302 M) and cyclometalated [N,C,N-Pt(II)] framework (0 — 0.0005035880649628604 M).
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