Interaction

uncurated

Interaction Scheme

Molecule

Mvcp
MVCP

c = 8.0 µM

Host

Cb7
CB7

c = 0.0 — 16.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 4.66⋅104 ± 5400.0 M-1
Kd =
logKa = 4.67 ± 0.05
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -26.65 ± 0.29 -6.37 ± 0.07
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 388.0 nm
𝛌em = 550.0 nm
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

L. Grimm, SupraBank 2024, Fluorescent Paracyclophanes: Unveiling Ultra-strong Binding with Cucurbit[8]uril in Aqueous Environments (dataset). https://doi.org/10.34804/supra.20240313527

Link: https://doi.org/10.34804/supra.20240313527
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

Link: https://suprabank.org/datasets/527

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of MVCP (0.00042918454935622315 M) and CB7 (0 — 0.0008583690987124463 M).