𝜈 | Molecule 1 : 1 Host | ||
Ka = | 1.23⋅104 | M-1 | |
Kd = | |||
logKa = | |||
T | 25.0 °C | ||
Energy | kJ mol-1 | kcal mol-1 | |||
---|---|---|---|---|---|
ΔG | = | -23.35 | -5.58 | ||
ΔH | = | -14.11 | -3.37 | ||
-TΔS | = | -9.24 | -2.21 | ||
J mol-1 K-1 | cal mol-1 K-1 | ||||
ΔS | = | 31.0 | 7.4 |
Detection Method: | Direct | ||
Assay Type: | Direct Binding Assay | ||
Technique: | Isothermal Titration Calorimetry | ||
Instrument: | Nanowatt Isothermal Titration Microcalorimeter Thermometric 2277 (Thermometric, Sweden) | ||
VCell | = | 500.0 𝜇L | |
VSyringe | = | 500.0 𝜇L | |
cmolecule | = | 15000.0 𝜇M syringe | |
cpartner | = | 5000.0 𝜇M cell | |
Ninjection | = | 40 | |
Vinjection | = | 12.0 𝜇L |
Solvent System | Buffer System | 0.05M Tris buffer pH 7 |
Solvents | water | |
Source of Concentration | ||
Total concentration | 50.0 mM | |
pH | 7.0 |
Citation: |
S. Xing, Q. Zhang, C. Zhang, Q. Zhao, H. Ai, D. Sun, SupraBank 2024, Isothermal Titration Calorimetry and Theoretical Studies on Host-guest Interaction of Ibuprofen with α-, β- and γ-Cyclodextrin (dataset). https://doi.org/10.34804/supra.20240816574 |
Link: | https://doi.org/10.34804/supra.20240816574 |
Export: | BibTex | RIS | EndNote |
Citation: |
S. Xing, Q. Zhang, C. Zhang, Q. Zhao, H. Ai, D. Sun, Journal of Solution Chemistry 2009, 38, 531–543. |
Link: | https://doi.org/DOI%2010.1007/s10953-009-9394-3 |
The plot depicts the binding isotherm simulation of a 1:1 interaction of Ibuprofen sodium (0.0016233766233766235 M) and β-CD (0 — 0.003246753246753247 M).