Interaction

uncurated

Interaction Scheme

Molecule

Untitled
NDP

c = 0.1 µM

Host

Cb7
CB7

c = 0.0 — 360.0 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 2.89⋅106 ± 2.60⋅105 M-1
Kd =
logKa = 6.46 ± 0.04
T 20.0 °C ≈ 293 K
Energy kJ mol-1 kcal mol-1
ΔG = -36.26 ± 0.22 -8.67 ± 0.05
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 296.0 nm
𝛌em = 330.0 nm
Detailed information about the solvation.
Solvent System Buffer System phosphate buffer - pH 7.4
Additives Potassium dihyd...
Sodium hydroxide
Source of Concentration
pH 7.4
Please find here information about the dataset this interaction is part of.
Citation:

C. Jia, Y. Zhong, X. Zhang, X. Liao, Y. Li, B. Yang, C. Gao, SupraBank 2024, Host–guest inclusion systems of nedaplatin with cucurbit[7]uril for improved in vitro antitumour activity (dataset). https://doi.org/10.34804/supra.20240828585

Link: https://doi.org/10.34804/supra.20240828585
Export: BibTex | RIS | EndNote
Please find here information about the scholarly article describing the results derived from that data.
Citation:

C. Jia, Y. Zhong, X. Zhang, X. Liao, Y. Li, B. Yang, C. Gao, J Incl Phenom Macrocycl Chem 2020, 97, 99–107.

Link: https://doi.org/10.1007/s10847-020-00988-x
Export: BibTex | RIS | EndNote |

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of NDP (6.9204152249134946e-06 M) and CB7 (0 — 1.3840830449826989e-05 M).