Interactions as Host or Guest 89
Actions / Info |
|
Molecule |
|
Molecule |
|
Partner |
|
Partner |
|
log Ka |
Medium |
T / °C |
Supplement |
|
|
DMF
|
|
DMF
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.07
|
|
25.0
|
|
|
|
(R)-Glycidyl...
|
|
(R)-Glycidyl...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.68
|
Deuterium Oxide
|
25.0
|
|
|
|
2-Butanol
|
|
2-Butanol
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.88
|
Deuterium Oxide
|
25.0
|
|
|
|
Tetrahydropyran
|
|
Tetrahydropyran
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.78
|
|
25.0
|
|
|
|
Isopropanol
|
|
Isopropanol
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.3
|
|
25.0
|
|
|
|
Tetrahydrofuran
|
|
Tetrahydrofuran
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.95
|
|
25.0
|
|
|
|
1,4-Dioxane
|
|
1,4-Dioxane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.5
|
Deuterium Oxide
|
25.0
|
|
|
|
4-METHYL-2-P...
|
|
4-METHYL-2-P...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.23
|
Deuterium Oxide
|
25.0
|
|
|
|
1,4-dioxene
|
|
1,4-dioxene
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.0
|
|
25.0
|
|
|
|
Oxepane
|
|
Oxepane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.17
|
|
25.0
|
|
|
|
2-PENTANOL
|
|
2-PENTANOL
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.92
|
Deuterium Oxide
|
25.0
|
|
|
|
Pyrrole
|
|
Pyrrole
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.6
|
|
25.0
|
|
|
|
2-Aminobutan...
|
|
2-Aminobutan...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.49
|
50mM ...
|
25.0
|
|
|
|
Acetonitrile
|
|
Acetonitrile
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.2
|
|
25.0
|
|
|
|
1,3,5-Trioxane
|
|
1,3,5-Trioxane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.23
|
|
25.0
|
|
|
|
Acetone
|
|
Acetone
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.04
|
|
25.0
|
|
|
|
(1-METHOXYET...
|
|
(1-METHOXYET...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.74
|
Deuterium Oxide
|
25.0
|
|
|
|
Cyclohexanone
|
|
Cyclohexanone
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
0.78
|
|
25.0
|
|
|
|
propylene gl...
|
|
propylene gl...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.23
|
Deuterium Oxide
|
25.0
|
|
|
|
Styrene oxide
|
|
Styrene oxide
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.64
|
water
|
25.0
|
|
|
|
1-Aminopropa...
|
|
1-Aminopropa...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.54
|
50mM ...
|
25.0
|
|
|
|
1-Phenylethanol
|
|
1-Phenylethanol
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.58
|
Deuterium Oxide
|
25.0
|
|
|
|
1-Phenyletha...
|
|
1-Phenyletha...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.98
|
50mM ...
|
25.0
|
|
|
|
4-Methylbenz...
|
|
4-Methylbenz...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.96
|
50mM ...
|
25.0
|
|
|
|
METHYL LACTATE
|
|
METHYL LACTATE
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.46
|
Deuterium Oxide
|
25.0
|
|
|
|
1-Methylbuty...
|
|
1-Methylbuty...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.28
|
Deuterium Oxide
|
25.0
|
|
|
|
Thiophene
|
|
Thiophene
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.31
|
|
25.0
|
|
|
|
1-Phenylethy...
|
|
1-Phenylethy...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.43
|
Deuterium Oxide
|
25.0
|
|
|
|
Acetone
|
|
Acetone
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.86
|
|
25.0
|
|
|
|
Propylene ca...
|
|
Propylene ca...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.85
|
|
25.0
|
|
|
|
Ethyl acetate
|
|
Ethyl acetate
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.36
|
|
25.0
|
|
|
|
N-ethylaceta...
|
|
N-ethylaceta...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.18
|
|
25.0
|
|
|
|
2-ethyloxirane
|
|
2-ethyloxirane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.76
|
Deuterium Oxide
|
25.0
|
|
|
|
2-Amino-1-ph...
|
|
2-Amino-1-ph...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.83
|
50mM ...
|
25.0
|
|
|
|
Imidazole
|
|
Imidazole
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.84
|
|
25.0
|
|
|
|
2-Methyl-3-p...
|
|
2-Methyl-3-p...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
5.18
|
water
|
25.0
|
|
|
|
trans-dimeth...
|
|
trans-dimeth...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.48
|
Deuterium Oxide
|
25.0
|
|
|
|
Oxetane
|
|
Oxetane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.37
|
|
25.0
|
|
|
|
Propylene ca...
|
|
Propylene ca...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.79
|
|
25.0
|
|
|
|
cis-2,3-Dime...
|
|
cis-2,3-Dime...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.47
|
Deuterium Oxide
|
25.0
|
|
|
|
2,2-Dimethox...
|
|
2,2-Dimethox...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.17
|
|
25.0
|
|
|
|
2,2-Dimethyl...
|
|
2,2-Dimethyl...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.45
|
Deuterium Oxide
|
25.0
|
|
|
|
N-ethylaceta...
|
|
N-ethylaceta...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.33
|
|
25.0
|
|
|
|
2-(pent-4-en...
|
|
2-(pent-4-en...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.76
|
water
|
25.0
|
|
|
|
SEC-BUTYLAMINE
|
|
SEC-BUTYLAMINE
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.11
|
50mM ...
|
25.0
|
|
|
|
1,4-Dioxane
|
|
1,4-Dioxane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.59
|
|
25.0
|
|
|
|
1,3-Dioxolane
|
|
1,3-Dioxolane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.45
|
|
25.0
|
|
|
|
2-(pent-4-en...
|
|
2-(pent-4-en...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.76
|
Deuterium Oxide
|
25.0
|
|
|
|
Diethylether
|
|
Diethylether
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.52
|
Deuterium Oxide
|
25.0
|
|
|
|
Ethanol
|
|
Ethanol
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.56
|
|
25.0
|
|
|
|
DMSO
|
|
DMSO
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.88
|
|
25.0
|
|
|
|
Diethylether
|
|
Diethylether
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.58
|
|
25.0
|
|
|
|
1,3-dioxane
|
|
1,3-dioxane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.32
|
|
25.0
|
|
|
|
DMF
|
|
DMF
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.89
|
|
25.0
|
|
|
|
Methyldioxolane
|
|
Methyldioxolane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.91
|
|
25.0
|
|
|
|
2-Methyl-3-p...
|
|
2-Methyl-3-p...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.95
|
Deuterium Oxide
|
25.0
|
|
|
|
Ethanol
|
|
Ethanol
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.63
|
|
25.0
|
|
|
|
Styrene oxide
|
|
Styrene oxide
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.39
|
Deuterium Oxide
|
25.0
|
|
|
|
Furan
|
|
Furan
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.17
|
|
25.0
|
|
|
|
2-Methyloxirane
|
|
2-Methyloxirane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.72
|
Deuterium Oxide
|
25.0
|
|
|
|
1,2,4-Triazole
|
|
1,2,4-Triazole
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.61
|
|
25.0
|
|
|
|
(Methylsulfo...
|
|
(Methylsulfo...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.82
|
50mM ...
|
25.0
|
|
|
|
Oxetane
|
|
Oxetane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.39
|
|
25.0
|
|
|
|
Cyclopentene...
|
|
Cyclopentene...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.13
|
Deuterium Oxide
|
25.0
|
|
|
|
2,2-Dimethox...
|
|
2,2-Dimethox...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.15
|
|
25.0
|
|
|
|
Styrene oxide
|
|
Styrene oxide
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.08
|
water
|
25.0
|
|
|
|
DMSO
|
|
DMSO
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.11
|
|
25.0
|
|
|
|
1,3-Dioxolane
|
|
1,3-Dioxolane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.41
|
|
25.0
|
|
|
|
Dimethoxymet...
|
|
Dimethoxymet...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.72
|
|
25.0
|
|
|
|
2-Methyl-3-p...
|
|
2-Methyl-3-p...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
5.0
|
water
|
25.0
|
|
|
|
3-Chloro-1,2...
|
|
3-Chloro-1,2...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.08
|
Deuterium Oxide
|
25.0
|
|
|
|
2-Methyloxirane
|
|
2-Methyloxirane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.43
|
Deuterium Oxide
|
25.0
|
|
|
|
1,3-Dioxolan...
|
|
1,3-Dioxolan...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.82
|
Deuterium Oxide
|
25.0
|
|
|
|
Solketal
|
|
Solketal
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.63
|
Deuterium Oxide
|
25.0
|
|
|
|
Benzyl glyci...
|
|
Benzyl glyci...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.74
|
Deuterium Oxide
|
25.0
|
|
|
|
Thiane
|
|
Thiane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.08
|
|
25.0
|
|
|
|
1-Phenyl-1,2...
|
|
1-Phenyl-1,2...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.76
|
Deuterium Oxide
|
25.0
|
|
|
|
2-Amino-2-ph...
|
|
2-Amino-2-ph...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.88
|
50mM ...
|
25.0
|
|
|
|
EPICHLOROHYDRIN
|
|
EPICHLOROHYDRIN
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.94
|
Deuterium Oxide
|
25.0
|
|
|
|
Styrene oxide
|
|
Styrene oxide
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
4.11
|
water
|
25.0
|
|
|
|
Acetonitrile
|
|
Acetonitrile
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.2
|
|
25.0
|
|
|
|
GLYCIDOL
|
|
GLYCIDOL
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.56
|
Deuterium Oxide
|
25.0
|
|
|
|
Glycidyl met...
|
|
Glycidyl met...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.53
|
Deuterium Oxide
|
25.0
|
|
|
|
Cyclohexene ...
|
|
Cyclohexene ...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
1.76
|
Deuterium Oxide
|
25.0
|
|
|
|
1,2-Butylene...
|
|
1,2-Butylene...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.79
|
Deuterium Oxide
|
25.0
|
|
|
|
Dimethyl car...
|
|
Dimethyl car...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
3.15
|
|
25.0
|
|
|
|
Nitromethane
|
|
Nitromethane
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.04
|
|
25.0
|
|
|
|
Oxazole
|
|
Oxazole
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
2.13
|
|
25.0
|
|
|
|
2-Methyl-3-p...
|
|
2-Methyl-3-p...
|
|
anti-Amide N...
|
|
anti-Amide N...
|
|
5.25
|
water
|
25.0
|
|