Dataset curated
- DOI:
- https://doi.org/10.34804/supra.20210928109
- Title:
- Synthesis of New Trisulfonated Calix[4]arenes Functionalized at the Upper Rim, and Their Complexation with the Trimethyllysine Epigenetic Mark
- Description:
- A synthetic route to produce a new family of trisulfonated calix[4]arenes bearing a single group, selectively introduced, that lines the binding pocket is reported. Ten examples, including new sulfonamide and biphenyl-substituted hosts, each with additional binding elements, demonstrate the tuning of guest affinities and selectivities. NMR titrations in phosphate-buffered water show that one of the new hosts binds to the modified amino acid trimethyllysine with the highest affinity and selectivity observed to date.
| Citation: |
K. D. Daze, F. Hof, M. C. F. Ma, F. Pineux, SupraBank 2025, Synthesis of New Trisulfonated Calix[4]arenes Functionalized at the Upper Rim, and Their Complexation with the Trimethyllysine Epigenetic Mark (dataset). https://doi.org/10.34804/supra.20210928109 |
| Link: | https://doi.org/10.34804/supra.20210928109 |
| Export: | BibTex | RIS | EndNote |
| Views | Downloads | Citations |
|---|---|---|
| 10138 | 0 | 0 |
| Citation: |
K. D. Daze, M. C. F. Ma, F. Pineux, F. Hof, Org. Lett. 2012, 14, 1512–1515. |
| Link: | https://doi.org/10.1021/ol300243b |
| Export: | BibTex | RIS | EndNote | |
- Creators:
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Kevin D. Daze
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Manuel C. F. Ma
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Florent Pineux
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Fraser Hof
- Contributers:
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Mary Maguire
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