Dataset curated

DOI:
https://doi.org/10.34804/supra.20210928345 Cc Cc by 4.0
Title:
Efficient Complexation of N-Acetyl Amino Acid Carboxylates in Water by an Artificial Receptor:  Unexpected Cooperativity in the Binding of Glutamate but Not Aspartate
https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/jacsat/2005/jacsat.2005.127.issue-30/ja052699k/production/images/large/ja052699kn00001.jpeg
Description:
A new tris-cation 1 binds N-acetyl amino acid carboxylates in water even at millimolar salt concentrations with Kass ≈ 103 M-1 due to a clustering of electrostatic interactions. Binding is efficient enough to allow a naked-eyed detection using an indicator displacement assay. Furthermore, receptor 1 shows an unexpected 2:1 complex formation with strong positive cooperativity with glutamate but not aspartate.
Citation:

C. Schmuck, L. Geiger, SupraBank 2024, Efficient Complexation of N-Acetyl Amino Acid Carboxylates in Water by an Artificial Receptor:  Unexpected Cooperativity in the Binding of Glutamate but Not Aspartate (dataset). https://doi.org/10.34804/supra.20210928345

Link: https://doi.org/10.34804/supra.20210928345
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Citation:

C. Schmuck, L. Geiger, J. Am. Chem. Soc. 2005, 127, 10486–10487.

Link: https://doi.org/10.1021/ja052699k
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Creators:
Orcidid | Ror | Carsten Schmuck
Orcidid | Ror | Lars Geiger
Contributers:
Orcidid | Ror | Rui Kang | DataManager

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