Dataset curated

DOI:
https://doi.org/10.34804/supra.20240322531 Cc Cc by 4.0
Title:
Calorimetric and spectroscopic investigations of interactions between cucurbituril Q7 and gemcitabine in aqueous solutions
https://static-content.springer.com/image/art%3A10.1007%2Fs10973-018-7295-7/MediaObjects/10973_2018_7295_Fig1_HTML.gif
Description:
Studies on the interactions between cucurbituril Q7 and gemcitabine (Gem) hydrochloride in water were carried out using isothermal titration calorimetry (ITC) and electrospray ionization–mass spectrometry (ESI-MS). According to ITC and ESI-MS, the formation of this complex occurs in both the solution containing excess gemcitabine and the solution containing excess cucurbituril Q7. ITC results confirm the formation of a thermodynamically stable supramolecular complex with stoichiometry 1:1. The inclusion mechanism of Gem inside the cucurbituril macromolecule is spontaneous ( $$\Delta G < 0$$ Δ G < 0 ). This process is exothermic ( $$\Delta H < 0$$ Δ H < 0 ) and is characterized by the loss of entropy ( $$\Delta S < 0$$ Δ S < 0 ).
Citation:

A. Stepniak, B. Palecz, A. Buczkowski, P. Urbaniak, SupraBank 2024, Calorimetric and spectroscopic investigations of interactions between cucurbituril Q7 and gemcitabine in aqueous solutions (dataset). https://doi.org/10.34804/supra.20240322531

Link: https://doi.org/10.34804/supra.20240322531
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Citation:

A. Buczkowski, A. Stepniak, P. Urbaniak, B. Palecz, J Therm Anal Calorim 2018, 134, 595–607.

Link: https://doi.org/10.1007/s10973-018-7295-7
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Creators:
Orcidid | Ror | Adam Buczkowski
Orcidid | Ror | Artur Stepniak
Orcidid | Ror | Pawel Urbaniak
Orcidid | Ror | Bartlomiej Palecz
Contributers:
Orcidid | Ror | Paersis Weslie | DataManager
Subjects:
physical and theoretical chemistry condensed matter physics

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