Dataset curated

DOI:
https://doi.org/10.34804/supra.2021092860 Cc Cc by 4.0

Title:
Multianalyte Sensing of Addictive Over-the-Counter (OTC) Drugs

https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/jacsat/2013/jacsat.2013.135.issue-40/ja407722a/production/images/large/ja-2013-07722a_0010.jpeg

Description:
A supramolecular sensor array composed of two fluorescent cucurbit[n]uril-type receptors (probe 1 and probe 2) displaying complementary selectivities was tested for its ability to detect and quantify drug-related amines. The fluorimetric titration of the individual probes showed highly variable and cross-reactive analyte-dependent changes in fluorescence. An excellent ability to recognize a variety of analytes was demonstrated in qualitative as well as quantitative assays. Importantly, a successful quantitative analysis of several analytes of interest was achieved in mixtures and in human urine. The throughput and sensitivity surpass those of the current state-of-the-art methods that usually require analyte solid-phase extraction (SPE). These results open up the opportunity for new applications of cucurbit[n]uril-type receptors in sensing and pave the way for the development of simple high-throughput assays for various drugs in the near future.

Citation:

T. Minami, N. A. Esipenko, B. Zhang, L. Isaacs, P. Anzenbacher, A. Akdeniz, SupraBank 2024, Multianalyte Sensing of Addictive Over-the-Counter (OTC) Drugs (dataset). https://doi.org/10.34804/supra.2021092860

Link: https://doi.org/10.34804/supra.2021092860
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Citation:

T. Minami, N. A. Esipenko, A. Akdeniz, B. Zhang, L. Isaacs, P. Anzenbacher Jr., J. Am. Chem. Soc. 2013, 135, 15238–15243.

Link: https://doi.org/10.1021/ja407722a
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Creators:
Orcidid | Ror | Tsuyoshi Minami
Orcidid | Ror | Nina A. Esipenko
Orcidid | Ror | Ali Akdeniz
Orcidid | Ror | Ben Zhang
Orcidid | Ror | Lyle Isaacs
Orcidid | Ror | Pavel Anzenbacher

Contributers:
Orcidid | Ror | Laura Grimm | DataManager

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