Interaction Scheme
Molecule
MDAP
c = 1.5 µM
Host
CB7
c = 0.0 — 7.5 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 4.40⋅105 | ± 1.00⋅104 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -32.21 | ± 0.06 | -7.7 | ± 0.01 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 338.0 nm | ||
| 𝛌em | = | 449.0 nm | ||
| Ibound⁄Ifree | = | 1.5 | ||
Detailed information about the solvation.
| Solvent System | Buffer System | sodium phosphate with NaCl pH-7.0 |
| Solvents | water | |
| Additives | sodium chloride | 100.0 mM |
| Source of Concentration | estimated | |
| pH | 7.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
A. E. Kaifer, V. Sindelar, M. A. Cejas, F. M. Raymo, SupraBank 2024, Tight inclusion complexation of 2,7-dimethyldiazapyrenium in cucurbit[7]uril (dataset). https://doi.org/10.34804/supra.20210928292 |
| Link: | https://doi.org/10.34804/supra.20210928292 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
V. Sindelar, M. A. Cejas, F. M. Raymo, A. E. Kaifer, New J. Chem. 2005, 29, 280. |
| Link: | https://doi.org/10.1039/B418017H |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of MDAP (4.545454545454545e-05 M) and CB7 (0 — 9.09090909090909e-05 M).
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