Interaction Scheme
Molecule
1,4-Dihydroxybenzene
c = 0.0 — 100.0 µM
Host
CB8
c = 10.0 µM
Cofactor
MDAP
c = 10.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.30⋅104 | M-1 | |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -23.48 | -5.61 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Associative Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 420.0 nm | ||
| 𝛌em | = | 450.0 nm | ||
Detailed information about the solvation.
| Solvent System | Single Solvent |
| Solvent | water |
| pH | 7.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
W. M. Nau, F. Biedermann, D. Hathazi, SupraBank 2024, Associative chemosensing by fluorescent macrocycle–dye complexes – a versatile enzyme assay platform beyond indicator displacement (dataset). https://doi.org/10.34804/supra.20210928360 |
| Link: | https://doi.org/10.34804/supra.20210928360 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
F. Biedermann, D. Hathazi, W. M. Nau, Chem. Commun. 2015, 51, 4977–4980. |
| Link: | https://doi.org/10.1039/c4cc10227d |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of 1,4-Dihydroxybenzene (0.0015384615384615385 M) and CB8 (0 — 0.003076923076923077 M).
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