𝜈 | Molecule 1 : 1 Host | ||
Ka = | 3.20⋅109 | ± 5.00⋅108 | M-1 |
Kd = | |||
logKa = | |||
T | 25.0 °C | ||
Energy | kJ mol-1 | kcal mol-1 | |||
---|---|---|---|---|---|
ΔG | = | -54.26 | ± 0.39 | -12.97 | ± 0.09 |
ΔH | = | -90.0 | ± 2.0 | -21.51 | ± 0.48 |
-TΔS | = | 36.0 | ± 2.0 | 8.6 | ± 0.48 |
J mol-1 K-1 | cal mol-1 K-1 | ||||
ΔS | = | -120.7 | ± 6.7 | -28.9 | ± 1.6 |
Detection Method: | Competitive | ||
Assay Type: | Competitive Binding Assay | ||
Technique: | Isothermal Titration Calorimetry | ||
Instrument: | MicroCal VP-ITC | ||
VCell | = | 1400.0 𝜇L | |
VSyringe | = | 350.0 𝜇L | |
Molecule: | syringe | ||
Partner: | cell | ||
Indicator: | cell |
Solvent System | Single Solvent |
Solvent | water |
Citation: |
M. V. Rekharsky, T. Mori, C. Yang, Y. H. Ko, N. Selvapalam, H. Kim, D. Sobransingh, A. E. Kaifer, S. Liu, L. Isaacs, W. Chen, S. Moghaddam, M. K. Gilson, K. Kim, Y. Inoue, SupraBank 2024, A synthetic host-guest system achieves avidin-biotin affinity by overcoming enthalpy-entropy compensation (dataset). https://doi.org/10.34804/supra.20210928129 |
Link: | https://doi.org/10.34804/supra.20210928129 |
Export: | BibTex | RIS | EndNote |
Citation: |
M. V. Rekharsky, T. Mori, C. Yang, Y. H. Ko, N. Selvapalam, H. Kim, D. Sobransingh, A. E. Kaifer, S. Liu, L. Isaacs, et al., Proceedings of the National Academy of Sciences 2007, 104, 20737–20742. |
Link: | https://doi.org/10.1073/pnas.0706407105 |
Export: | BibTex | RIS | EndNote |
The plot depicts the binding isotherm simulation of a 1:1 interaction of 1-(hydroxymethyl)-ferrocene (6.25e-09 M) and CB7 (0 — 1.25e-08 M).