Interaction Scheme
Molecule
L-Arg
Host
sCx4
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 2830.0 | ± 110.0 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -19.7 | ± 0.1 | -4.71 | ± 0.02 |
| ΔH | = | -25.9 | ± 0.1 | -6.19 | ± 0.02 |
| -TΔS | = | 6.2 | ± 0.2 | 1.48 | ± 0.05 |
| J mol-1 K-1 | cal mol-1 K-1 | ||||
| ΔS | = | -20.8 | ± 0.7 | -5.0 | ± 0.2 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | ||
| Assay Type: | Direct Binding Assay | ||
| Technique: | Isothermal Titration Calorimetry | ||
| Molecule: | syringe | ||
| Partner: | syringe | ||
Detailed information about the solvation.
| Solvent System | Complex Mixture | |
| Solvents | water | |
| Additives | hydrochloric acid | 100.0 mM |
| pH | 1.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
J. Morel, N. Morel-Desrosiers, N. Douteau-Guével, A. W. Coleman, SupraBank 2025, Complexation of the basic amino acids lysine and arginine by three sulfonatocalix[n]arenes (n = 4, 6 and 8) in water: microcalorimetric determination of the Gibbs energies, enthalpies and entropies of complexation (dataset). https://doi.org/10.34804/supra.20210928207 |
| Link: | https://doi.org/10.34804/supra.20210928207 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
N. Douteau-Guével, A. W. Coleman, J.-P. Morel, N. Morel-Desrosiers, J. Chem. Soc., Perkin Trans. 2 1999, 629–634. |
| Link: | https://doi.org/10.1039/A806855K |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of L-Arg (0.007067137809187279 M) and sCx4 (0 — 0.014134275618374558 M).
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