𝜈 | Molecule 1 : 1 Host | ||
Ka = | 4545.0 | ± 144.0 | M-1 |
Kd = | |||
logKa = | |||
T | 30.0 °C | ||
Energy | kJ mol-1 | kcal mol-1 | |||
---|---|---|---|---|---|
ΔG | = | -21.23 | ± 0.08 | -5.07 | ± 0.02 |
ΔH | = | -13.2 | ± 0.2 | -3.15 | ± 0.05 |
-TΔS | = | -7.9 | -1.89 | ||
J mol-1 K-1 | cal mol-1 K-1 | ||||
ΔS | = | 26.1 | 6.2 |
Detection Method: | Direct | ||
Assay Type: | Direct Binding Assay | ||
Technique: | Isothermal Titration Calorimetry | ||
Molecule: | syringe | ||
Partner: | syringe |
Solvent System | Buffer System | 40 mM phosphate pH-7.4 |
Solvents | water | 100.0 % |
Additives | Disodium hydrog... | 30.2 mM |
Sodium dihydrog... | 9.8 mM | |
Source of Concentration | ||
Total concentration | 40.0 mM | |
pH | 7.4 |
Citation: |
K. D. Daze, F. Hof, C. S. Beshara, M. C. F. Ma, T. Pinter, A. Ibraheem, S. A. Minaker, R. J. M. Courtemanche, R. E. Campbell, SupraBank 2024, Supramolecular hosts that recognize methyllysines and disrupt the interaction between a modified histone tail and its epigenetic reader protein (dataset). https://doi.org/10.34804/supra.20210928174 |
Link: | https://doi.org/10.34804/supra.20210928174 |
Export: | BibTex | RIS | EndNote |
Citation: |
K. D. Daze, T. Pinter, C. S. Beshara, A. Ibraheem, S. A. Minaker, M. C. F. Ma, R. J. M. Courtemanche, R. E. Campbell, F. Hof, Chem. Sci. 2012, 3, 2695. |
Link: | https://doi.org/10.1039/C2SC20583A |
Export: | BibTex | RIS | EndNote | |
The plot depicts the binding isotherm simulation of a 1:1 interaction of AARKSAPY (0.0044004400440044 M) and sCx4 (0 — 0.0088008800880088 M).