Interaction Scheme
Molecule
norfloxacin
c = 10.0 µM
Host
sCx4
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.19⋅104 | M-1 | |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -23.26 | -5.56 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 305.0 nm | ||
Detailed information about the solvation.
| Solvent System | Buffer System | 500 mM phosphate pH-3.0 |
| Solvents | water | |
| Additives | Sodium dihydrog... | |
| Phosphoric acid | ||
| Disodium hydrog... | ||
| Source of Concentration | ||
| Total concentration | 500.0 mM | |
| pH | 3.0 |
Please find here information about the dataset this interaction is part of.
| Citation: |
J. Chao, K. Song, H. Wang, Z. Guo, B. Zhang, T. Zhang, SupraBank 2024, Study on the inclusion interaction of p-sulfonatocalix[n]arenes with norfloxacin (dataset). https://doi.org/10.34804/supra.2021092884 |
| Link: | https://doi.org/10.34804/supra.2021092884 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
J. Chao, K. Song, H. Wang, Z. Guo, B. Zhang, T. Zhang, Physics and Chemistry of Liquids 2016, 55, 579–588. |
| Link: | https://doi.org/10.1080/00319104.2016.1250270 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of norfloxacin (0.0016806722689075631 M) and sCx4 (0 — 0.0033613445378151263 M).
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